Differing views on antiviral remedy efficacy in sufferers co-infected with HIV and HCV
Two separate research offered at the moment at The Worldwide Liver Congress™ 2016 in Barcelona, Spain have supplied various conclusions concerning the efficacy of direct-acting antivirals (DAAs) amongst sufferers co-infected with HIV and Hepatitis C virus (HCV). GEHEP-SEIMC and HEPAVIR examine group information: On this potential, multi-cohort examine from Spain, researchers have proven that HIV negatively impacts charges of response to DAA medicines in folks co-infected with HCV. Sufferers with HIV and HCV co-infection had an 11% decrease charge of reaching SVR12 (or the eradication of HCV from the physique at 12 weeks) with interferon-based DAAs in comparison with sufferers with solely HCV. These co-infected sufferers taking interferon-free DAAs had a 6% decrease charge of reaching SVR12 in comparison with sufferers with solely HCV. "Our examine demonstrates the impression of HIV co-infection on the effectiveness of DAA-...